NCT03217916Unknown不适用
Evaluation of Kidney Injury Biomarkers in Women Suffering From Preeclampsia
Woman's Health University Hospital, Egypt0 个研究点目标入组 40 人开始时间: 2017年8月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 40
- 主要终点
- Magnitude of renal injury caused by preclampsia
研究概览
简要总结
we found different pattern of podocyte glycoproteins and kidney injury biomarkers in urine specimens between preeclampsia and pregnancy complicated with chronic hypertention compared with normotensive pregnant controls.abnormally elevayed urine biomarkers in severe preeclampsia were completely or prtially reduced 6-8 weaks after delivery to levels comparable with those of normal pregnant subjects.
详细描述
Study design:
- Type of the study: Aprospective cross sectional study .All patients will be enrolled in the study after obtaining a written consent.
- Setting: This study will be carried in the Emergency room of Assiut university Hospital &Luxor International Hospital
Statistical Methods:
Inclusion criteria:
- the presence of informed consent
- Prim gravid or multi gravid <5
- age:18-35 ys
- Singleton pregnancy with gestational age >34weeks.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •the presence of informed consent
- •Prim gravid or multi gravid <5
- •age:18-35 ys
- •Singleton pregnancy with gestational age >34weeks
排除标准
- •Serious maternal illness.
- •women with pregnancy complicated by nephritic syndrome, diabetic mellitus, or gestational diabetes
- •women known to have renal disease
结局指标
主要结局
Magnitude of renal injury caused by preclampsia
时间窗: within 6 month postpartum
the changes in renal chemistry (serum creatinine and blood urea) in pregnant women with severe preclampsia
次要结局
- Apgar score of the deliverd fetus(1, 5 and 10 minutes after delivery)
研究者
Hisham Ahmed El-Sayed Abou-Taleb
Hisham A. Abou-Taleb
Woman's Health University Hospital, Egypt
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