Effects of Physical-Cognitive Training With Different Task Models in Parkinson's Disease With Mild Cognitive Impairment

Not Applicable

Completed

• Conditions: Mild Cognitive Impairment; Parkinson Disease

• Registration Number: NCT05172661
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

The present study will characterize exercise model effects (integrated model vs. consecutive model) of physical-cognitive exercise on dual-task walking control in Parkinson's disease with mild cognitive impairment.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-11-26
• Study First Submitted: 2021-11-29
• Study First Submitted QC: 2021-12-12
• Study First Posted: 2021-12-29
• Primary Completion: 2022-06-30
• Study Completion: 2022-09-30
• Status Verified: 2023-01
• Last Update Submitted: 2023-02-01
• Last Update Posted: 2023-02-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 27

Inclusion Criteria

• a diagnosis of idiopathic Parkinson's disease
• have decreased cognitive functions but do not interfere with functional independence
• Montreal Cognitive Assessment (MoCA): 21-25
• able to walk independently without walking devices for at least 10 meters and with the ability to turn 180°

Exclusion Criteria

• a diagnosis of dementia
• other diseases that may influence cognitive functions or walking performance
• a history of brain surgery
• modification of the medication during the exercise intervention

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Change from baseline dual-task walking performance at 8 weeks	8 weeks
Change from baseline Montreal Cognitive Assessment (MoCA) score at 8 weeks	8 weeks	MoCA: 0-30 points, higher scores mean a better outcome
Fall frequency	20 weeks

Trial Locations

Locations (1)

National Taiwan University; 🇨🇳 Taipei, Taiwan