A study of the structure of a newly identified hormone in the blood to help diagnose the cause of chest pain.

Not Applicable

Completed

• Conditions: acute myocardial infarction; Cardiovascular - Coronary heart disease

• Registration Number: ACTRN12609000039280
• Lead Sponsor: Health Research Council of New Zealand

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-01-19
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

70 patients presenting to the Accident & Emergency department or the Coronary Care Unit of Christchurch Hospital with typical chest pains (<8 hours from onset), clear evidence of ST segment elevation on Electrocardioegraph (ECG) together with a rise of plasma Troponin levels

Exclusion Criteria

Unable to give informed consent Unable to comply with study requirements

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome of this study will be the identification on brain natriuretic peptide signal peptide (BNP-SP) amino acid structure. Using specific immunoassay, peptide sequencing, mass spectrometry, high performance liquid chromatography (HPLC), we will determine the amino acid structure of plasma B-type Natriuretic Peptide signal peptide (BNP-SP).[One blood sample of 50mls taken within 8 hours of onset of symptoms of a heart attack]

Secondary Outcome Measures

Name	Time	Method
n/a[n/a]