Effect of ingestion of yacon syrup in huma

Not Applicable

• Conditions: Appetite; Women; F02.830.071; M01.975

• Registration Number: RBR-33wf46
• Lead Sponsor: Fundação Universidade Estadual do Ceará FUNECE

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-03-12
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

Women; between 20 and 40 years old; do not present chronic self-reported diseases; have a body mass index of eutrophy or obesity grade I; regular menstrual cycle.

Exclusion Criteria

Pregnancy or lactation; hysterectomy performed; current smoker or in the last 30 days; users of illicit drugs; daily consumption of ethanol higher than 15g; current or last 30 days use of hypoglycemic, lipid-lowering, antibiotic and anti-inflammatory medications, laxatives or weight-loss medications; have inflammatory diseases such as inflammatory bowel disease (Crohn's disease, ulcerative colitis); endocrinopathy carrier’s (cushing's syndrome, hypothyroidism), cancer carrier’s, having celiac disease or lactose intolerance; have constipation history; present current consumption and in the last 30 days of fiber and fructooligosaccharides supplementation.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improvement of the postprandial response of the plasma biomarkers of appetite after ingestion of yacon syrup compared to placebo;verified by blood dosage of glucagon-like peptide 1 (GLP1) and ghrelin at times 0, 15, 30, 45, 60, 90, 120 and 180. The improvement will be verified if there is statistical significance (p <0.05) in the comparison of the areas under the curve between treatment A (syrup intake) and treatment B (placebo intake), a difference of at least 50% between treatments is expected.

Secondary Outcome Measures

Name	Time	Method
Improvement of the postprandial response of serum glycemia, serum insulin, serum triglycerides and subjective sensation of satiety after yacon syrup ingestion compared to placebo; verified by glucose, insulin and triglycerides blood dosages and self-reporting on satiety at times 0, 15, 30, 45, 60, 90, 120 and 180. The improvement will be verified if there is statistical significance (p <0, 05) in the comparison of the areas under the curve between treatment A (syrup intake) and treatment B (placebo intake), a difference of at least 50% between treatments is expected.