NCT04840511进行中（未招募）不适用
The Effect of Perioperative Lidocaine Infusion on Neutrophil Extracellular Trapping in the Patients Undergoing the Robot-assisted Prostatectomy
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Concentration of citrullinated histone3
研究概览
简要总结
This study will be done to investigate perioperative lidocaine infusion on neutrophil extracellular trapping in the patients undergoing the robot-assisted prostatectomy.
详细描述
Neutrophil extracellular trapping by analyzing the meyloperoxidase, neutrophil elastase, citrullinated histone3
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 75 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •patients scheduled robot-assisted prostatectomy
排除标准
- •lidocaine allergy Hx
- •hemodynamic unstable patients
- •weight < 40kg
- •arrhythmia or bradycardia
研究组 & 干预措施
lidocaine group
Experimental
The study group receives perioperative lidocaine infusion with general anesthesia for robot-assisted prostatectomy
干预措施: lidocaine group (Drug)
control group
Placebo Comparator
The control group receives normal saline infusion with with general anesthesia for robot-assisted prostatectomy
干预措施: control group (Drug)
结局指标
主要结局
Concentration of citrullinated histone3
时间窗: 24 hours after surgery
This will be obtained using ELISA.
次要结局
- Concentration of meyloperoxidase(24 hours after surgery)
- Concentration of neutrophil elastase(24 hours after surgery)
研究者
Young Eun Moon
Associate professor
The Catholic University of Korea
研究点 (1)
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