Direct extubation onto high flow nasal prongs post cardiac surgery versus standard treatment in obese patients with a body mass index (BMI) of >/= 30: A randomised controlled trial

Not Applicable

Completed

• Conditions: Cardiac surgery; Respiratory - Other respiratory disorders / diseases; Cardiovascular - Other cardiovascular diseases; Diet and Nutrition - Obesity; Atelectasis; Obesity

• Registration Number: ACTRN12610000942055
• Lead Sponsor: Amanda Corley

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-11-04
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 162

Inclusion Criteria

Male or female >/= 18 years
BMI >/= 30
Post on-cardiopulmonary bypass cardiac surgery

Exclusion Criteria

Patient refusal
Patients requiring direct extubation onto NIPPV
Pneumothorax
Patients unable to tolerate HFNP
Those requiring tracheostomy
Patients extubated as part of end of life treatment

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduction in atelectasis post cardiac surgery[Chest radiography will be performed on Day 1 and 5 post surgery and scored for severity of atelectasis using a validated scoring system (Radiological Atelectasis Score) by a radiologist who is blinded to patient identity and treatment]

Secondary Outcome Measures

Name	Time	Method
Reduction in hypoxaemia (as measured by PaO2/FiO2 ratio)[Pao2/Fio2 will be calculated from any arterial blood gases taken as part of clinical care during the first 24hrs from return from surgery];Improvement in patient dyspnoea score[Dyspnoea Visual Analogue Scale - measured at 1, 8 and 12 hours post extubation];Reduction in Respiratory rate[Respiratory rate will be collected hourly from the patient's observation sheet for the first 24 hrs after surgery.]