Comparison of Spinal Anesthesia Adjuvant and Quadratus Lumborum Block on the Opioid Requirement and Perioperative Pain of Laparoscopic Kidney Transplant Donor
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Postoperative pain
研究概览
简要总结
This study aims to compare the effectiveness of spinal anesthesia adjuvant and quadratus lumborum block on the opioid requirement and perioperative pain on patients undergoing laparoscopic kidney transplant donor.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 18-65 years undergoing laparoscopic donor nephrectomy
- •Patients with BMI ≤ 35 kg/m2
- •Patients with American Society of Anesthesiology (ASA) physical status 1-2
- •Patients who are willing to participate in this study
排除标准
- •Cardiovascular disease (uncontrolled stage 2 hypertension, heart failure, arrhytmia)
- •Recent onset cerebrovascular diseasae of < 3 months
- •Infection on spinal site
- •Coagulopathy
- •Elevated intracranial pressure
- •Severe renal or liver dysfunction
- •Valvular heart disease or atrioventricular block
研究组 & 干预措施
Quadratus lumborum block
Patients in this arm will receive quadratus lumborum block with 20-30 ml of 0.25% Bupivacaine after induction of anesthesia and after operation.
干预措施: Quadratus Lumborum Block (QLB) (Procedure)
Quadratus lumborum block
Patients in this arm will receive quadratus lumborum block with 20-30 ml of 0.25% Bupivacaine after induction of anesthesia and after operation.
干预措施: General Anesthesia (Procedure)
Spinal anesthesia adjuvant
Patients in this arm will receive 10 mg 0.5% hyperbaric Bupivacaine, 100 mcg Morphine, 100 mcg Sulfas Atropine, and 0.9% normal saline to total volume of 4 ml before induction of anesthesia.
干预措施: Spinal anesthesia adjuvant (Procedure)
Spinal anesthesia adjuvant
Patients in this arm will receive 10 mg 0.5% hyperbaric Bupivacaine, 100 mcg Morphine, 100 mcg Sulfas Atropine, and 0.9% normal saline to total volume of 4 ml before induction of anesthesia.
干预措施: General Anesthesia (Procedure)
结局指标
主要结局
Postoperative pain
时间窗: Hour 2, 6, 12, and 24
Postoperative pain measured with Numerical Rating Scale (NRS) during rest and movement.
Opioid requirement
时间窗: Hour 2, 6, 12, and 24
Morphine requirement on Patient-Controlled Analgesia (PCA).
次要结局
未报告次要终点
研究者
Dita Aditianingsih
Prof. Dr. dr. Dita Aditianingsih, Sp.An-TI., Subsp.T.I.(K).
Indonesia University