Assessment of the Health Improvement of Obese Patients After Fecal Microbiota Transplantation (FMT)
Not Applicable
Completed
- Conditions
- Obesity; Familial
- Registration Number
- NCT04579263
- Lead Sponsor
- Federal Research and Clinical Center of Physical-Chemical Medicine
- Brief Summary
Search for mechanisms of the effect of fecal microbiota transplantation on patients with obesity
- Detailed Description
1. To select recipients of fecal samples according to eligibility criteria;
2. To perform fecal microbiota transplantation for patients with obesity;
3. To analyze the efficacy of fecal microbiota transplantation for patients with obesity within six months after therapy.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 2
Inclusion Criteria
- age of patients - from 18 to 75 years, both sexes;
- patients with obesity (body mass index ≥40
- patient's informed consent to perform fecal microbiota transplantation
Exclusion Criteria
- presence of a concomitant chronic infectious disease or malignancy
- patients with a proven allergy to foods not excluded from the donor's diet
- absence of the patient for one or more intermediate stages of the examination.
- informed refusal to continue therapy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Change in insulin sensitivity within FMT, 6 months after FMT] 6 months after FMT participants will undergo euglycaemic glucose clamp study
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
Endocrinology Research Centre, Moscow
🇷🇺Moscow, Russian Federation
Federal Research and Clinical Center of Physical-Chemical Medicine, Moscow (FRCC PCM)
🇷🇺Moscow, Russian Federation
Endocrinology Research Centre, Moscow🇷🇺Moscow, Russian Federation