Macroscopic and Molecular Changes in Knee Muscular - Tendon Unit in Response to Acute Resistant Load

Not Applicable

• Conditions: Physical Exertion
• Interventions: Other: Exercise; Other: No exercise

• Registration Number: NCT03332693
• Lead Sponsor: Hillel Yaffe Medical Center

Brief Summary

The aim of this study is to determine whether individuals differ one from the other in their genetic, cellular, systemic, structural and functional response to acute exercise.

Detailed Description

Not available

Study Timeline

• Status Verified: 2017-11
• Study Start: 2017-11
• Study First Submitted: 2017-11-02
• Study First Submitted QC: 2017-11-02
• Last Update Submitted: 2017-11-02
• Study First Posted: 2017-11-06
• Last Update Posted: 2017-11-06
• Primary Completion: 2019-11
• Study Completion: 2019-11

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

• Healthy adults

Exclusion Criteria

• Unhealthy adults

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Light exercise	Exercise	Volunteers will participate in one short exercise
Heavy exercise	Exercise	Volunteers will participate in heavy exercise
No exercise	No exercise	Volunteers will not participate in exercise

Primary Outcome Measures

Name	Time	Method
Genetic polymorphism changes in knee muscles	One year	Genetic analysis will be made through a blood test and biopsy of knee muscle and results will be compared

Trial Locations

Locations (1)

Hillel Yaffe Medical Center; 🇮🇱 Hadera, Israel