to find out the parameter of heart ultrasound which can predict post reperfusion syndrome (complication that may develop during organ transplant) during liver transplant.

Completed

• Conditions: Liver disorders in diseases classified elsewhere,

• Registration Number: CTRI/2022/09/045448
• Lead Sponsor: Institute of liver and biliary sciences

Brief Summary

Patients undergoing liver transplant frequently display considerable physiological changes during the procedures as a result of both the disease process and the surgery. Haemodynamic changes occurring during liver transplantation are severe and rapid. Eechocardiography is a non invasive monitor that provides information regarding dynamic function of heart, volume status, contractility, regional wall motion. Vital information which can be gathered from standard echocardiography views includes biventricular function, valvular function, volume status, pericardial abnormalities, intra-cardiac thrombus, pulmonary embolism, ventricular outflow obstruction, cardiac tamponade.

As per our literature,echocardiographic parameters have never been studied to predict the post reperfusion syndrome during living donor liver transplantation. Hence, we are conducting this study to find the echocardiographic parameters which can predict the post reperfusion syndrome during living donor liver transplantation.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-09-15
• Study Completion: 2023-04-20
• Last Update Posted: 2023-05-27

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 50

Inclusion Criteria

All patients undergoing LDLT.

Exclusion Criteria

• Patient refusal Patients undergoing double transplant at same setting.
• Patients with Acute Liver Failure.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
echocardiographic parameter to predict post reperfusion syndrome during living donor liver transplantation	Baseline, Dissection phase, 10min peclampingof IVC, 10 min postclamping of IVC, Reperfusion, at biliary construction

Secondary Outcome Measures

Name	Time	Method
echocardiographic parameter to predict time to achieve hemodynamic stability	Postoperative period

Trial Locations

Locations (1)

Institute of liver and biliary sciences; 🇮🇳 Delhi, DELHI, India

Institute of liver and biliary sciences

🇮🇳Delhi, DELHI, India

Dr Vaishali Agarwal

Principal investigator

8840661695

shagun30agarwal@gmail.com