Skin autofluorescence and regular physical activity in health and disease

Completed

Conditions: Acute Coronary Syndrome
Heart attack
10019280

Registration Number: NL-OMON46053

Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 190

Inclusion Criteria

- written informed consent for study participation
- 18 yearsor older;For the different groups there will be specific inclusion criteria next to the criteria mentioned above. The competitive athletes and regularly training people have to fill in the PAR-Q questionnaire. They can only participate if they answer no to all questions. ;Competitive athletes:
- Training for more than 10 hours a week
- Performing an axial sport (involvement of components of jumping and running);regularly trained people
- Performing physical activity on a regular basis (regular is at least once a week for more than 60 min).
Control group
- Sedentary healthy people, performing physical activity that characterize sedentary behavior (1,0 - 1,5 MET (Metabolic Equivalent of Task)).;People who had a cardiovascular event and are going to follow a rehabilitation program
- People participating in a rehabilitation program in Beatrixoord

Exclusion Criteria

- people not able or willing to sign informed consent
- tattoo on the lower part of the arm
- dark skin
- diabetes
- renal failure, eGFR<60
- known auto immune disease
- recent infection (<3 months) serious enough to result in hospitalisation

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary parameter is SAF. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary study parameters are the frequency (times per week) and duration<br /><br>(minutes per session) of physical activity, the structure and function of the<br /><br>Achilles tendons, and vascular compliance. </p><br>