Predictive markers of gestational diabetes mellitus in first and early second trimester of pregnancy

Recruiting

• Conditions: Gestational diabetes mellitus; Pregnancy and Childbirth

• Registration Number: ISRCTN13134709
• Lead Sponsor: niversity of Athens

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-03-20
• Last Update Posted: 12 November 2018
• Study Completion: 2019-05-31

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 150

Inclusion Criteria

1. Female
2. Age over 18 years
3. Singleton pregnancies

Exclusion Criteria

1. Age under 18 years
2. Multiple pregnancy
3. Pre-existing type 1 or type 2 diabetes mellitus
4. Chronic hypertension
5. Preeclampsia, eclampsia
6. Hypothyroidism
7. Pre-existing renal or hepatic impairment
8. Other chronic diseases (e.g. valvular heart disease)
9. Vaginal bleeding (e.g. placental abruption)
10. Special diets (e.g. lactose intolerance)
11. Inadequate monitoring during pregnancy

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Serum adiponectin is measured using blood samples at 11-13 (plus six days) weeks of pregnancy<br>2. Serum leptin measured using blood samples at 11-13 (plus six days) weeks of pregnancy

Secondary Outcome Measures

Name	Time	Method
1. Serum sex hormone-binding globulin (SHBG) are measured using blood samples at 11-13 (plus six days) weeks of pregnancy<br>2. Lipid profile (total cholesterol, triglycerides, HDL cholesterol, LDL cholesterol) are measured usng blood samples at 11-13 (plus six days) weeks of pregnancy<br>3. Atherogenic markers (LDL cholesterol, HDL cholesterol, triglycerides, HDL cholesterol and total cholesterol, HDL cholesterol) are measured using blood samples at 11-13 (plus six days) weeks of pregnancy