Association between Brown Adipose Tissue and metabolic health in patients with manifest vascular disease or at high risk for cardiovascular events.
Completed
- Conditions
- Vetweefselbrown adipose tissue
- Registration Number
- NL-OMON41498
- Lead Sponsor
- niversitair Medisch Centrum Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
Patients participating in the SMART cohort (protocol number 96-048).
Exclusion Criteria
- Pregnancy or lactation.
- Mentally incapacitated subjects.
- Claustrophobia.
- Waist circumference >200cm.
- Metallic devices in the body of the participant such as cardioverter-defibrillators (AICD/ICD), pacemakers, cochlear implants, implanted insulin pumps, endoscopic (gastric) or aneurysm (brain) clips according to the UMCU MRI guidelines. (https://richtlijn.mijnumc.nl/Beeld/MRI/Documents/MRI%20Veiligheid%20MRI%20contra-indicaties.pdf)
- Patients with HIV infection.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Reproducibility of measuring BAT volume (mL) within the supraclavicular fossae<br /><br>by determining inter-scan, inter-observer and intra-observer variability.<br /><br><br /><br>Addendum.<br /><br>Adipose tissue estimated Fat Fraction. From this a volume estimation of brown<br /><br>adipose tissue can be derived. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Not applicable. </p><br>