Heart Failure and Regional Specific Exercise Training Stimulus
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 发起方
- 试验地点
- 2
- 主要终点
- Subject Adherence & Compliance
研究概览
简要总结
The aim of this study is to determine whether heart failure patients can tolerate a four-weeks of a new exercise training regimen that targets peripheral tissues (Regional Specific Training Stimulus-RSTS) and has been show to produce significant benefits in aerobic capacity and strength in healthy subjects aged 70+years who were at risk for losing functional independence.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 55 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Men and women between the ages of 55 and 90
- •Diagnosed with heart failure (NYHA class II-III)
- •Receiving optimal medical therapy
- •Sedentary (≤ 30 min/wk structured physical activity)
- •Peak VO2 between 10 and 30 mL/kg/min.
排除标准
- •Oxygen dependent
- •Recent medications changes (within 3 months)
- •Fixed-rate pacemakers
- •Uncontrolled hypertension
- •Type I diabetes
- •Organ transplant
- •Bariatric surgery
- •Renal failure (stage 4 or 5)
结局指标
主要结局
Subject Adherence & Compliance
时间窗: 4 Weeks
The number of training sessions attended and successfully completed divided by the total number of planned sessions
One Repetition Maximum (1RM)
时间窗: 4 Weeks
Skeletal muscle strength assessed using a one repetition maximum (1RM) measurement obtained for the seated row, chest press, leg press and handgrip.
Senior Fitness Test
时间窗: 4 Weeks
The Senior Fitness Test is a previously validated battery of 6 physical tasks of daily living used to assess strength, flexibility and endurance in order to detect and predict future limitations in functional capacity. The test is designed to evaluate physical fitness domains including upper-body strength (Arm Curl), lower-body strength (Chair Sit-Stand), upper and lower body flexibility (Back Scratch and Chair Sit and Reach), balance and coordination (8 foot Up and Go), and endurance (Six Minute Walk).
次要结局
未报告次要终点