Evaluation of the sedative effect of nasal dexmedetomidine in endoscopic procedures
Phase 3
- Conditions
- Indution of sedation for endoscopy in billiary disorders.Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
- Registration Number
- IRCT2015103011398N9
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Inclusion criteria's are: Age 18-65 years, both sex, having informed consent for entry to the study, ASA physical status class I-III
Exclusion criteria's include: Age less than 18 and over than 65 years, ASA class over than III, history of open surgery in last week before endoscopy, chronic users of opiates & benzodiazepines, bradycardia (HR<45), systolic blood pressure less than 90 mmhg, cardiac conduction abnormality, patients using B-blockers & calcium channel blockers, patients with prolonged QT interval, active bleeding of upper or lower GI tract, patients with hemodynamic instability, pregnant patients, advanced liver insufficiency
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method evel of sedation. Timepoint: Every two min after intervention. Method of measurement: Richmond agitation sedation scale.
- Secondary Outcome Measures
Name Time Method Total dose of midazolam and fentanyl useage. Timepoint: End of procedure. Method of measurement: Sum of these drugs in mg/kg.