The Effect of Intranasal Dexmedetomidine Premedication on the Minimum Alveolar Concentration of Sevoflurane for the Insertion of Laryngeal Mask Airway in childre

Phase 4

Completed

• Conditions: Induction and maintenance of general anaesthesia in children; Anaesthesiology - Anaesthetics

• Registration Number: ACTRN12613000462785
• Lead Sponsor: Yusheng Yao

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-04-23
• Study Completion: 2013-11-28
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

ASA 1 and 2 patients of either gender of the age 3- 7 years undergoing elective strabismus surgery under general anaesthesia which can be performed with LMA insertion

Exclusion Criteria

airway malformations, clinical evidence of patients with difficult airway, asthma or any sign of upper respiratory tract infection.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To determine and compare the Minimum Alveolar Concentration of sevoflurane for LMA insertion in children by using Dixon and Massey up and down method[At or one minute after LMA insertion]

Secondary Outcome Measures

Name	Time	Method
the incident of adverse events were recorded in each patient's diary/health record for the trial e.g.laryngospasm,gapping,cough[Timepoint: during the period of Inhalation induction];the incidence of emergence agitation was evauated by the Pediatric Anesthesia Emergence Delirium Scale (PAED)[Participants will be followed for duration of PACU stay,an expected average of 2h];Ramsay Sedation Score[after intranasal administration every 10min until 60min];Parent Satisfaction was evauated by the VAS Scale(0-10)[at the time of children discharge from PACU ]