High-flow nasal oxygenation in sedated lung transplant patients during transbronchial biopsy

Not Applicable

Recruiting

• Conditions: ung transplant patients; Oxygenation during transbronchial biopsy; Lung transplant patients; Anaesthesiology - Anaesthetics; Respiratory - Other respiratory disorders / diseases

• Registration Number: ACTRN12619000292178
• Lead Sponsor: Dr Charles Cartwright

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-02-26
• Last Update Posted: 15 July 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Aged >=18 years old
Lung transplant patients
Undergoing transbronchial biopsy
English speaking and able to provide informed consent

Exclusion Criteria

Aged <18 years old
Non-lung transplant patients
Participants not having transbronchial biopsies conducted
Non-English speaking and unable to provide informed consent
Pre-procedure: respiratory failure/cardiovascular failure/recent pneumothorax (<2 weeks)
Chest tube in-situ
Reduced level of consciousness
Pregnant women
Unable to have the procedure carried out with a propofol infusion
Significant aspiration risk (e.g. gastroparesis/severe GORD) or unable to have the procedure done without endotracheal intubation
Unsuitable for nasal cannulae – recent nasal surgery/epistaxis, significant nasal or sinus issue, marked septal deviation, basal skull fracture
Clinical need for an LMA/intubation

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The proportion of participants experiencing a desaturation (defined as SpO2 <94%)[At any point during the bronchoscopy - from the point that the monitoring equipment (including pulse oximeter) and oxygen delivery device are attached in the operating theatre to the point at which they are removed. <br><br>Observations will be automatically uploaded onto the study computer at regular intervals (e.g. every 10 seconds for oxygen saturation). ]