The effect of L-arabinose on the glycaemic and insulinemic response after consumption of a liquid product.
- Conditions
- Diabetes type 2metabolic diseases10018424
- Registration Number
- NL-OMON45701
- Lead Sponsor
- Wageningen Universiteit
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 24
- 18-35 years old while signing the informed consent
- good Dutch writing, speaking, understanding
- healthy: as judged by the participant
- stable body weight, i.e. no reported weight loss or weight gain of >5kg in the two months prior to the screening session
- normal Fasting glucose concentration <6.1mmol/L, measured by finger prick
- normal hemoglobine (Hb) concentration >8.5 mmol/L for men and >7.5 mmol/L for females, measured by finger prick
- women being pregnant or lactating
- allergy, intolerance or oversensitivity for food products
- having a history of medical or surgical events that may affect the study outcome
- having gastro-intestinal problems
- medical drug use that may affect the study outcome
- current antibiotics usage or in the two months prior to the screening session
- not willing to eat or drink the test products
- use of dietary supplements that may affect the study outcome
- currently using a slimming or medically prescribed diet or having used one in the two months prior to the screening session
- excessive alcohol consumption (*21 glasses/week on average)
- planning to change physical activity pattern during the study period
- having blood vessels that are too difficult for inserting a cannula, as judged by the study nurse
- recent blood donation (<1 month prior to the first testday of the study)
- planning to donate blood as a blood donor during the study
- not having a general practitioner
- being an employee or student performing their thesis or internship of Wageningen University, division of Human Nutrition
- current participation in other research
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The primary outcomes are glycaemic and insulinemic response.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Secondary outcomes are:<br /><br>1) appetite ratings,<br /><br>2) subsequent ad libitum energy intake,<br /><br>3) tolerance of the treatments,<br /><br>4) gastro-entero endocrine markers,<br /><br>5) L-arabinose in the blood, and<br /><br>6) excretion of L-arabinose in urine.</p><br>