Effect of Quince Paste on Heartburn and Regurgitation in Pregnancy

Not Applicable

Conditions: Gastroesophageal reflux disease (GERD).
Gastro-oesophageal reflux disease without oesophagitis

Registration Number: IRCT2014120120170N1

Lead Sponsor: College of Traditional Medicine of Tehran University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: Female

Target Recruitment: 140

Inclusion Criteria

1) Pregnant patients aged 18 to 35 years old.
2) Gestational age 12 to 34 weeks.
3) Not responsiveness to 2-week lifestyle modification.
4) Not taking any drug for the complains in the leading week to the study.
5) Giving informed consent.
6) Secured follow-up.

Exclusion criteria:
1) Unbearable heartburn sensation.
2) Previously Approved GERD leading to pregnancy, such as peptic ulcer, duodenal ulcer, IBS, and so on.
3) High-risk pregnancies.
4) Pregnancy complications, such as AUB, threatened abortion, etc.
5) History of drug abuse, alcohol and smoking.
6) History of chronic diseases.
7) History of infertility.
8) Assisted reproductive technology pregnancy.
9) History of respiratory diseases.
10) History of allergic reaction to quince products.

Exclusion Criteria

Not provided

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severity of regurgitation. Timepoint: Before intervention, 2 and 4 weeks after commencement, at the end of intervention. Method of measurement: Myoclinic questionnaire.;Severity of epigastric pain. Timepoint: Before intervention, 2 and 4 weeks after commencement, at the end of intervention. Method of measurement: Myoclinic questionnaire.;Frequency of regurgitation. Timepoint: Before intervention, 2 and 4 weeks after commencement, at the end of intervention. Method of measurement: Myoclinic questionnaire.;Frequency of heartburn. Timepoint: Before intervention, 2 and 4 weeks after commencement, at the end of intervention. Method of measurement: Myoclinic questionnaire.;Severity of heartburn. Timepoint: Before intervention, 2 and 4 weeks after commencement, at the end of intervention. Method of measurement: Myoclinic questionnaire.;Frequency of epigastric pain. Timepoint: Before intervention, 2 and 4 weeks after commencement, at the end of intervention. Method of measurement: Myoclinic questionnaire.

Secondary Outcome Measures