To compare the effect of ondansetron and granisetron on spinal anaesthesia induced decreased BP and decreased HR in elderly patients
Phase 4
Not yet recruiting
- Conditions
- Health Condition 1: 4- Measurement and Monitoring
- Registration Number
- CTRI/2021/10/037135
- Lead Sponsor
- Dr Sarvjeet kaur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients scheduled for elective surgeries under spinal anaesthesia aged between 50-70years of either gender, giving valid informed and written consent , belong to ASA grade 1 and 2
Exclusion Criteria
Patients with any contraindication to spinal anaesthesia .
Patients with any history of anaphylaxis to local anaesthetics and allergy to study drugs.
Obese patients with BMI >30kg/m2.
Patients with coronary artery disease, MI, valvular heart disease, hypertension and DM.
Patients having history of psychiatric illness or substance abuse or chronic alcoholic.
Patients taking antihypertensive medications.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study the effect of ondansetron in prevention of hypotension and bradycardia after spinal anaesthesia <br/ ><br>To study the effect of granisetron in prevention of hypotension and bradycardia after spinal anaesthesia <br/ ><br>To study the effect of normal saline in prevention on hypotension and bradycardia after spinal anaesthesia <br/ ><br>To compare the above 3 outcomesTimepoint: <br/ ><br>2hours post-operatively
- Secondary Outcome Measures
Name Time Method To compare the effect of ondansetron with granisetron in prevention of hypotension and bradycardia in patients undergoing spinal anaesthesiaTimepoint: 2hours postoperatively