Metabolic availability of L-lysine from milk powder using indicator amino acid oxidation technique
- Conditions
- Digestion
- Registration Number
- NL-OMON20970
- Lead Sponsor
- FrieslandCampina
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 19
Adults:
Apparently healthy adult male volunteers
Normal Hb > 13g/l
Age: 20-40 years
Normal BMI between 18.5 to 25 kg/m2
Physical activity level <1.5 assess nu validated questionnaire
Subject to agree to avoid smoking and alcohol consumption for the entire study duration
Subject willing to participate and adhere to the study protocol for 7 consecutive weeks
Children:
Children 6-10 years of age, both sexes
Apparently healthy
BAZ between -2SD and 1 SD
Children and parents willing to participate and adhere to adaptation diets for 5 consecutive weeks
Adults:
History of smoking or taking other leisure drugs in past 3 months and/or study duration
Consumption of alcohol in the previous 24 hr and/or in study duration
History of antibiotics in last month
On iron, protein, multivitamin, and/ or any other supplementation therapy in past 3 months
Unstable weight over last 3 months
Use of medications known to affect intestinal functions and protein metabolism
Participation in any nutritional intervention study in last 3 months
History of food allergy
History of acute illness. gastointestinal, respiratory tract symptoms of fever in the past 1 week
diagnosed with any acute or chronic medical conditions
Children:
Any acute or chronic illnesses
Menarche
Weight loss in last 1 month
Worm infestation as assessed by stool test
History of antibiotics in last month
On iron, protein, multivitamin, and/ or any other supplementation therapy in past 3 months
Use of medications known to affect intestinal functions and protein metabolism
History of food allergy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Adults: true metabolic availability of L-lysine in two milk powders compared with a reference crystalline amino acid mixture<br>Children: relative metabolic availability of L-lysine in two milk powders
- Secondary Outcome Measures
Name Time Method