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Clinical analgesic effect and Mechanism of Massage manipulation in the treatment of knee Osteoarthritis

Phase 1
Conditions
Knee osteoarthritis
Registration Number
ITMCTR1900002311
Lead Sponsor
Guanghua Hospital, Shanghai University of Chinese Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

(1) Repeated knee joint pain in the past 1 month; (2)X-ray films (standing position or load-bearing position) showed narrowing of joint space, subcartilage osteosclerosis and / or cystic degeneration, and formation of osteophyte at the edge of the joint; (3) Age = 50 years; (4) Morning stiffness time = 30 min; (5) there is bone friction sound (feeling) during the activity. Osteoarthritis of knee joint can be diagnosed by meeting the diagnostic criteria of 1 + (any 2 of 2, 3, 4 and 5).

Exclusion Criteria

(1) there was skin damage around the knee joint; (2) patients with history of knee surgery and severe trauma; (3) patients with secondary OA, complicated with rheumatoid arthritis, gouty arthritis, infectious arthritis and other joint diseases; (4) patients with diabetes mellitus, systemic infection, severe abnormal liver and kidney function, malignant tumor and other diseases; (5) the patients were treated with non-steroidal anti-inflammatory drugs and intra-articular injection in the past 3 months; (6) those who were allergic to drugs in this study; (7) pregnant or lactating women; (8) patients with mental disorder or cognitive dysfunction; (9) those who did not accept or could not adhere to the treatment plan of this study.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
PPT;Chinese version of pain self-efficacy questionnaire;Pain visual analog score;
Secondary Outcome Measures
NameTimeMethod
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