Sudden versus Gradual Weaning from NIV support in preterm neonates :- A Randomized Controlled Trial . - NI

niversity College of Medical Sciences AND GTB HOSPITA0 个研究点目标入组 0 人开始时间: 待定最近更新: 2024年7月22日

试验速览

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•All preterm neonates (28 to 36 week) on NIV Support and met the weaning readiness criteria .
•1. Clinically stable neonate on NIV,PEEP of less than equal to 6cm H2O,Fio2 less than equal to 0.35percent, Maintaining Spo2 90-95percent for a minimum of 12 hours.
•2. Normal work of breathing:no persistent tachypnea (more than 60 breaths for more than 2hr ),no marked retractions .
•3. Hemodynamically stable .
•4.NO APNEA associated with bradycardia or cyanosis with more than 2 episode in 12hr or more than 3 in 24hr with at least one requiring bag and mask ventilation .
•5.Not currently treated for Patent ductus arteriosus.
•6.Tolerated time off NIV during nursing cluster care for up to 5 to 10 minutes.
•7. Pip of less than equal to 15 cm H20 and backup respiratory rate of less than equal to 50 percent of total respiratory rate.

•Preterm neonates with chromosomal defects and severe congenital anomalies including congenital heart disease , neurological malformations , chest wall or airway abnormalities and lung hypoplasia .

发起方

niversity College of Medical Sciences AND GTB HOSPITA