Effect of Caffeine for fast-track surgery and cognitive functions in children undergoing open heart surgery: a randomized, double-blind, controlled study.

Not Applicable

Recruiting

• Conditions: Paediatrics; Anaesthesia

• Registration Number: PACTR202308786657562
• Lead Sponsor: Mansoura university children hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-08-02
• Last Update Posted: 4 March 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Children aged between 1-7 year
American Society of Anesthesiologists physical status II
undergoing scheduled elective simple congenital heart disease correction

Exclusion Criteria

history of clinically significant pulmonary hypertension
hepatic, renal
neurological dysfunction(history of stroke, documented increased intracranial tension, history of intra cranial hemorrhage)
mental retardation
known allergy to drugs
emergency surgeries
redo surgeries

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Extubation time (minutes)

Secondary Outcome Measures

Name	Time	Method
Emergence delirium (ED will be assessed with the Pediatric Anesthesia Emergence Delirium (PAED) scale, which consists of 5 psychometric items describing emergence behavior, scores ranging from 0 to 20). ;Postoperative FLACC pain score .;Hemodynamic parameters such as heart rate (HR), Mean arterial blood pressure (MAP) ;The total dose of fentanyl consumption ;Time to first rescue analgesia; Intensive care unit (ICU) length of stay;Preoperative and post operative MMSE score.