A comparison of desflurane - dexmedetomidine with muscle relaxation versus desflurane - dexmedetomidine without muscle relaxants in patients undergoing surgery for supratentorial lesions
Phase 2
- Conditions
- Health Condition 1: null- American society of Anesthesiologists grade I/II, Glasgow Coma Scale 15/15
- Registration Number
- CTRI/2016/05/006945
- Lead Sponsor
- KEM Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Closed to Recruitment of Participants
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Age â?? 18 - 60 years
American Society of Anaesthesiologists grade I/II
Glasgow Coma Scale 15/15
Exclusion Criteria
No consent
Pregnant and lactating patients
Patient on beta blockers, sick sinus syndrome
Hypersensitivity to bupivacaine/dexmedetomidine/propofol/atarcurium
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time taken to achieve Alderete score 9, Time taken for eye opening, Time taken for extubation, Time taken for orientationTimepoint: monitored every 15 mins for 1st hour, and then at 60 mins, 90 and 120 minutes after extubation
- Secondary Outcome Measures
Name Time Method Intraoperative and post operative hemodynamic stability, requirement of fentanyl, dexmedetomidine and propofol, Brain Relaxation ScoreTimepoint: every 10 minutes in intraoperative period, monitored every 15 mins for 1st hour, and then at 60 mins, 90 and 120 minutes after extubation