MedPath

Deep Brain Stimulation induced Cortical Modulation in Tourette syndrome

Not Applicable
Conditions
F95.2
Combined vocal and multiple motor tic disorder [de la Tourette]
Registration Number
DRKS00018838
Lead Sponsor
Klinik für Psychiatrie und Psychotherapie, Uniklinik Köln
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
11
Inclusion Criteria

Suficient German language skills
- Age between 18 and 65 Jahren
- Ability to give informed consent
- Diagnosis Tourette syndrome (ICD 10)
- Thalamic deep brain stimulation

Exclusion Criteria

- Suicidal tendencies
- Psychotic symptoms
- Drug addiction
- Pregnancy or nursing period
- Severe internistic illness
- Severe neurological disorder
- Mental retardation
- Accomodation via PsychKG §14
- Use of benzodiazepine
- Withdrawal of informed consent

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Changes in EEG frequency bands evoked by thalamic deep brain stimulation. Recordings will follow an ABABAB design. The primary outcome is the EEG signal difference between on and off stimulation.
Secondary Outcome Measures
NameTimeMethod
Predicition of EEG changes by overlap of volumes of tissue activitated with specific thalamic nuclei.
© Copyright 2025. All Rights Reserved by MedPath