Sex Differences in Neuropeptide Y Serum, But Not in Fat Intake and Body Mass Index

Not Applicable

Completed

• Conditions: Nutrient Deficiency
• Interventions: Diagnostic Test: Neuropeptide Y examination

• Registration Number: NCT04650308
• Lead Sponsor: Universitas Sumatera Utara

Brief Summary

One's appetite has a role in controlling food intake and maintaining energy balance, but its effect on body metabolism related to obesity is still questionable. The purpose of this study was to determine the levels of neuropeptide Y in healthy people and to see differences in gender and anthropometric parameters. The hypothesis of this study was that there would be differences in neuropeptide Y levels in groups with gender and anthropometric parameter differences.

Detailed Description

One's appetite has a role in controlling food intake and maintaining energy balance, but its effect on body metabolism related to obesity is still questionable. The purpose of this study was to determine the levels of neuropeptide Y in healthy people and to see differences in gender and anthropometric parameters. The hypothesis of this study was that there would be differences in neuropeptide Y levels in groups with gender and anthropometric parameter differences. This study was a cross-sectional study involving 62 study subjects, male and female, who did not have chronic diseases or metabolic disorders. This research was conducted from April to September 2020. The parameters examined in this study were neuropeptide Y levels and anthropometric parameters. The statistical analysis performed was the Mann-Whitney test to see the differences between groups. The mean age of the research subjects was 40.48 ± 10.85 years, with the same ethnic distribution. The distribution of men and women was more women than men. Based on anthropometric examination, it was found that obesity nutritional status was more common in the female group than in the male group; however, serum neuropeptide Y levels were found to be significantly different between male and female groups (male group was higher).

Study Timeline

• Study Start: 2020-04-02
• Primary Completion: 2020-06-17
• Study Completion: 2020-09-10
• Status Verified: 2020-11
• Study First Submitted: 2020-11-23
• Study First Submitted QC: 2020-11-30
• Last Update Submitted: 2020-11-30
• Study First Posted: 2020-12-02
• Last Update Posted: 2020-12-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 62

Inclusion Criteria

• healthy groups for Neuropeptide Y Serum diagnosis

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Exclusion Criteria

• Non-healthy groups for Neuropeptide Y Serum diagnosis

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Healthy group	Neuropeptide Y examination	healthy men and women aged 20-60 years old.
Non-healthy group	Neuropeptide Y examination	pregnant women, nursing mothers, impaired kidney and liver function, chronic disease, or other metabolic disorders.

Primary Outcome Measures

Name	Time	Method
levels of neuropeptide Y	up to 2 weeks

Trial Locations

Locations (1)

Faculty of Medicine Universitas Sumatera Utara; 🇮🇩 Medan, North Sumatra, Indonesia