Cognitive Stimulation

Phase 2

Completed

• Conditions: Substance Use Disorders

• Registration Number: NCT01271413
• Lead Sponsor: Johns Hopkins University

Brief Summary

This research is being done to learn if computer tasks that challenge the brain (cognitively stimulating tasks) can improve memory and other types of thinking. The study will compare the effects of different versions of the computer tasks. It also will compare the task performance of different groups of people.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-12
• Study First Submitted: 2011-01-05
• Study First Submitted QC: 2011-01-05
• Study First Posted: 2011-01-06
• Primary Completion: 2013-07
• Study Completion: 2013-07
• Results First Submitted: 2013-11-23
• Results First Submitted QC: 2014-01-20
• Status Verified: 2014-03
• Results First Posted: 2014-03-07
• Last Update Submitted: 2014-03-25
• Last Update Posted: 2014-04-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 134

Inclusion Criteria

• age 18-55
• in methadone maintenance or healthy volunteers
• healthy

Exclusion Criteria

• Axis I disorder (except substance abuse and dependence in methadone maintenance patients)
• severe cognitive impairment
• serious untreated medical condition

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Working Memory	baseline, 7 weeks	Change in maximum number of digits correctly recalled in Digit Span Backwards task, from baseline to 7 weeks

Secondary Outcome Measures

Name	Time	Method
Episodic Memory	baseline, 7 weeks
Trail-making	baseline, 7 weeks
go/No-go	baseline, 7 weeks
Addiction Severity Index	baseline, 7 weeks
Delay Discounting	baseline, 7 weeks
Digit Symbol Substitution Test	baseline, 7 weeks

Trial Locations

Locations (1)

BPRU, Johns Hopkins Bayview Medical Center; 🇺🇸 Baltimore, Maryland, United States