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Prospective Study of Hormone Levels After Bariatric Surgery

Completed
Conditions
Obesity
Interventions
Procedure: Gastric bypass
Procedure: Gastric banding
Registration Number
NCT00627315
Lead Sponsor
Columbia University
Brief Summary

This project will study the effects of surgery for obesity on bone metabolism and hormones that regulate appetite.

Detailed Description

Subjects will be recruited from the outpatient obesity and surgical clinics at Columbia-Presbyterian Medical Center after they have chosen to undergo a surgical procedure. The groups will not be randomized. Rather, they will decide on their choice of surgery along with their physicians. The patients will be evaluated pre-operatively and followed post-operatively for 5 years.

Initial evaluation will include a complete history and physical examination, measurement of calcium, parathyroid hormone (PTH) and vitamin D, and assessment of skeletal health using markers of bone turnover and bone mineral density.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
236
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
SurgeryGastric bandingObese adult men and women who are undergoing bariatric surgery (gastric bypass or gastric banding).
SurgeryGastric bypassObese adult men and women who are undergoing bariatric surgery (gastric bypass or gastric banding).
Primary Outcome Measures
NameTimeMethod
Change in body weight5 years

linear mixed model analysis will be used to study change over time and between surgery

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Columbia University Medical Center

🇺🇸

New York, New York, United States

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