Bariatric procedures and changes in gut hormones and gastric passage

Completed

• Conditions: Gastric emptying; hormonal changes; 10017998

• Registration Number: NL-OMON44151
• Lead Sponsor: Rijnstate Ziekenhuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 15

Inclusion Criteria

- Age > 18 years
- Patient underwent a standard RYGB (S-RYGB), B-RYGB or EP-RYGB and is a mean responder (clinic mean Excess Weight Loss +/- 10% or mean Total Body Weight Loss +/- 5%).
- Patient is able to adhere to the study visit schedule and protocol requirements
- Patient is able to give informed consent and the consent must be obtained prior to any study procedures
- Patient had a follow-up period of at least one year after S-RYGB, B-RYGB or EP-RYGB without any complications

Exclusion Criteria

- Binge-eating or associated eating disorder
- Active drug or alcohol addiction
- Pregnancy and when giving breast feeding
- Gluten allergy
- Inability to stop medication that affects the motility of the upper gastrointestinal tract (anti-cholinergic drugs, prokinetics, theophylline, calcium blocking agents, opioids)
- Endocrine disease influencing gastric emptying (diabetes mellitus, hyper- or hypothyroidism)

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Gastric emptying rate and gut hormone levels in patients one year after S-RYGB,<br /><br>B-RYGB and EP-RYGB.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Excess weight loss (%EWL)</p><br>