To compare the effects of Macintosh direct laryngoscope versus Glidescope videolaryngoscope on the blood pressure and upper airway injury in patients with high blood pressure during general anaesthesia

Completed

• Conditions: Hypertensive patients undergoing surgery requiring orotracheal intubation

• Registration Number: CTRI/2017/08/009294
• Lead Sponsor: All India Institute of Medical SciencesNew Delhi

Brief Summary

The aim of the study is to compare the classic intubating device, the Macintosh direct laryngoscope with the Glidescope® videolaryngoscope for orotracheal intubation in hypertensive patients scheduled for surgery under general anaesthesia. The Primary outcome is to compare  hemodynamic responses (Blood pressure and heart rate) to orotracheal intubation using the Macintosh direct laryngoscope and the Glidescope® videolaryngoscope. The Secondary outcomes are  Total intubation time,   Number of intubation attempts, Complications during intubation and Postoperative airway morbidity assessed after 24 hrs - sore throat, hoarseness, dysphagia, and cough.

Fifty patients with hypertension controlled on antihypertensive medications scheduled for elective surgery under general anaesthesia requiring orotracheal intubation will be randomly divided into two groups of 25 each and assessed on the above mentioned outcomes.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-10-09
• Study Completion: 2015-10-30
• Last Update Posted: 2017-04-08

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Patients with hypertension controlled on antihypertensive medications scheduled for elective surgery under general anaesthesia requiring orotracheal intubation.

Exclusion Criteria

1.Age <18 yrs 2.History of coronary artery disease 3.History of difficult intubation 4.Difficult Airway 5.BMI>30 6.Cervicospinal disease 7.Otolaryngologic surgeries 8.Neurosurgery 9.Gastroesophageal reflux 10.Secondary hypertension.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparison of hemodynamic responses (Blood pressure and heart rate) to orotracheal intubation using the Macintosh direct laryngoscope and the Glidescope® videolaryngoscope.	1.Baseline | 2.Post induction | 3.Pre intubation | 4.At the time of intubation | 5.At 1,2,3,4,5 minutes following intubation

Secondary Outcome Measures

Name	Time	Method
1.Total intubation time	2.Number of intubation attempts

Trial Locations

Locations (1)

All India Institute of Medical Sciences,New Delhi; 🇮🇳 South, DELHI, India

All India Institute of Medical Sciences,New Delhi

🇮🇳South, DELHI, India

Vimi Rewari

Principal investigator

9818304880

vimirewari@gmail.com