Perioperative Analgesia for Knee Arthroplasty (PAKA) - a pilot randomised trial
Completed
- Conditions
- Muskuloskeletal, total knee arthroplasty, analgesiaMusculoskeletal DiseasesKnee Arthroplasty
- Registration Number
- ISRCTN29107680
- Lead Sponsor
- niversity of Warwick (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 46
Inclusion Criteria
All patients undergoing an elective primary unilateral total knee replacement (TKA) under the care of an orthopaedic consultant at University Hospitals Coventry and Warwickshire NHS Trust
Exclusion Criteria
1. Cognitive impairment, unable to complete questionnaire
2. Patients who lack capacity under the Mental Capacity Act 2005
3. Patients with pre-operative history of neruological abnormality in the ipsilateral leg e.g. history of stroke, neurogenic pain or previous nerve injury
4. Patients having spinal aneasthesia
5. Patients with specific contraindication to the analgesic agents used: Morphine, Ketorolac, Levobupivicaine
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Visual Analogue Scale at 18 hours post operation
- Secondary Outcome Measures
Name Time Method Serum Levobupivacaine levels pre & post retransfusion<br>1. Functional assessment: <br>1.1. Straight leg raise <br>1.2. Mobility assessed bed to chair 18 & 48 hours post operatively<br>2. Oxford Knee Score 6 weeks post operatively