Observation of clinical efficacy of Ying-Pi No.1 hand mask cream in the treatment of scleroderma
Phase 1
Completed
- Conditions
- scleroderma
- Registration Number
- ITMCTR2100005418
- Lead Sponsor
- The First Affiliated Hospital of Zhejiang Chinese Medicine University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
Patients who met the SSc classification diagnostic criteria of The American College of Rheumatology (ACR) in 2013(score 9 points) and whose skin involvement was in the stage of swelling and sclerosis.
Exclusion Criteria
Patients with important organ involvement, such as pulmonary interstitial disease, pulmonary hypertension, pericardial effusion or hypertrophic inflammatory myopathy, need more than 0.5mg/kg/day glucocorticoid treatment; Patients with renal crisis; Patients with arteriovenous thrombosis and diabetes-related gangrene; Patients with SSC-related gangrene infection; Local skin is extensively damaged and cannot be applied externally.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method mRSS;Number of loops Input branch diameter output branch diameter top diameter of loop length of loop malformation ratio number of shallow corrugated nipples;
- Secondary Outcome Measures
Name Time Method