The efficacy of ketamine in reducing postoperative pain in children undergoing cleft palate (CP) surgery
Phase 4
- Conditions
- Cleft palateCleft palate surgery , ketamine, paediatric, postoperative pain
- Registration Number
- TCTR20221024001
- Lead Sponsor
- Khon Kaen University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 46
Inclusion Criteria
Children age of 9 months to 6 years, ASA I to II, Undergoing elective palatoplasty and palatoplasty with other surgery e.g., cheiloplasty, myringotomy, etc.
Exclusion Criteria
Parents refusal, Children with mental retardation, Patient with contraindication of ketamine e.g., uncontrolled hypertension, increase intracranial pressure, increase intraocular pressure, etc., History of allergy to any of the study drugs, Chronic pain syndrome
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain score 0,15,30,45,60 minute post-operative FLACC scale
- Secondary Outcome Measures
Name Time Method Hemodynamic effect of ketamine 0,5,10,15,30 minute after drudged administration BP, HR, MAP,Time to first analgesic requirement in PACU minutes,Total analgesic consumption at PACU in PACU Total fentanyl administration in mcg IV,Emergence time time after discontinuation of anesthesia to successful extubation minute,Incidence of emergence delirium in PACU PAED score,Incidence of postoperative nausea and vomitting (PONV) in PACU dry heaves, nausea, vomitting,Parent's satisfaction in PACU rating score of 0-10