The immediate analgesia of acupuncture for biliary colic and the underlying peripheral-cerebral influence: a randomized controlled trial
- Conditions
- Biliary colic
- Registration Number
- ITMCTR2000003458
- Lead Sponsor
- Chengdu University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
(1) Age between 18 and 60 years and right-handed.
(2) Mild tenderness in the right upper abdomen, with Murphy's sign (-).
(3) Not taken any NSAIDs within two weeks.
(4) Signed informed consent.
(1) Calculus in bile duct.
(2) Acute cholecystitis, acute suppurative, gangrenous, incarcerated cholecystitis and perforation of gallbladder with diffuse peritonitis, etc.
(3) Serious complications or primary diseases such as cerebral, cardiovascular, liver, kidney, endocrine and hematopoietic system.
(4) Severe digestive system diseases, such as peptic ulcer, upper gastrointestinal hemorrhage, gastric tumor, Crohn's disease, irritable bowel syndrome, etc.
(5) Other causes of upper abdominal pain, such as gastritis, enteritis, pancreatitis, peritonitis, etc.
(6) White blood cells (WBCs)>15×10^9/L with systemic inflammatory response.
(7) Mental disorders such as serious anxiety and depression (the Zung Self-Rating Anxiety Scale (SAS) scores = 70 or the Zung Self-Rating Depression Scale (SDS) scores >=72);
(8) Taking other medications, such as analgesic drugs.
(9) Pregnancy or lactating women.
(10) Participating in any other clinical trials in the past three months.
(11) Received any acupuncture treatment in recent 1 month.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method umerical Rating Scale (NRS);
- Secondary Outcome Measures
Name Time Method ocal pain threshold at acupoints;the Chinese version of modified Massachusetts General Hospital Acupuncture Sensation Scale (C-MASS);the Zung Self-Rating Depression Scale;The 12-item Short Form Health Survey;fNIRS;the Zung Self-Rating Anxiety Scale;