Prediction of the Occurrence of Chronic Pain After Thoracotomy by Measuring Preoperative Skin Conductance (Pain Monitor Device)
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- Hopital Foch
- 入组人数
- 6
- 试验地点
- 2
- 主要终点
- Prediction of chronic pain
研究概览
简要总结
The skin conductance algesimeter (Pain Monitor™, Med-Storm Innovation AS, NO-0264 Oslo, Norway)) reflects the sympathetic nervous system by the measurement of the skin conductance of the palm of the hand. SCA detects nociceptive pain fast and continuously, specific to the individual, with higher sensitivity and specificity than other available objective methods.
The skin conductance response to a calibrated noxious stimulus varies among patients. It defines two types of people depending on its magnitude.
The investigators assume that the importance of skin conductance response to a noxious stimulus predicts the occurrence of chronic pain in patients operated by thoracotomy.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adult patients of both sexes
- •planned pulmonary resection for cancer performed by a posterolateral thoracotomy
- •thoracic epidural analgesia
排除标准
- •pregnancy,
- •morbid obesity,
- •insulin-dependent diabetes with dysautonomia,
- •inability to proceed with anesthesia using the BIS signal,
- •known allergy to remifentanil, propofol, atracurium or to levobupivacaine,
- •contra-indication to nefopam
- •contra-indication to ketoprofen
结局指标
主要结局
Prediction of chronic pain
时间窗: one year after surgery
Prediction of chronic pain by the measurement of skin conductance
次要结局
- Prediction of the postoperative pain(5 days postoperatively)
- Prediction of the postoperative antalgic requirement by the genetic study(One year after surgery)
- Prediction of the postoperative antalgic requirement(5 days postoperatively)
- Effect of remifentanil on skin conductance(One hour after anesthesia)