Gut Hormones After Meal Ingestion in Males Versus Females

Not Applicable

Completed

• Conditions: Normal Non-fluency
• Interventions: Other: Meal ingestion

• Registration Number: NCT01366781
• Lead Sponsor: Lund University

Brief Summary

The study hypothesis is that the release of gut hormones is increased proportionally to caloric load in each meal. Three different meals with different meal size will therefore be served and gut hormones determined.

Detailed Description

In healthy males and females, meals with 511, 743 and 1034 kcal will be given orally. Samples will be taken during the following 300 min and gut hormones (glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1) will be determined along with insulin and glucagon levels.

Study Timeline

• Study Start: 2011-05
• Study First Submitted: 2011-05-31
• Study First Submitted QC: 2011-06-02
• Study First Posted: 2011-06-06
• Primary Completion: 2014-02
• Study Completion: 2014-06
• Status Verified: 2014-09
• Last Update Submitted: 2014-09-29
• Last Update Posted: 2014-09-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

• Healthy status

Exclusion Criteria

• Diabetes
• Liver disease
• kidney disease
• thyroid disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Arm && Interventions

Group	Intervention	Description
Healthy males	Meal ingestion	Meal ingestion in healthy males
Healthy females	Meal ingestion	Meal ingestion in healthy females

Primary Outcome Measures

Name	Time	Method
Release of gut hormones	300 min

Secondary Outcome Measures

Name	Time	Method
Insulin secretion	300 min

Trial Locations

Locations (1)

Department of Clinical Sciences Lund, Lund University; 🇸🇪 Lund, Sweden