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Effect of vitamin D on the systolic blood pressure in hypertensivepatients with low vitamine D levels.

Completed
Conditions
systolic hypertension, vitamin D insufficiency.systole hypertensie, vitamine D insufficientie.
Registration Number
NL-OMON20826
Lead Sponsor
Dr. Y.W.J. Sijpkens, internist-nephrologistDrs. W.J. Liefers, hospital pharmacist in training.
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
100
Inclusion Criteria

1. The patient has signed an informed consent;

2. The patient is an adult male or female (age 18 yr or above);

Exclusion Criteria

1. Using prescribed cholecalciferol supplement (equal to or more than 400 IE = 10 microg/day) after t = -2 months;

2. MDRD below normal for age/gender;

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Systolic blood pressure.
Secondary Outcome Measures
NameTimeMethod
1. Plasma renin concentration;<br /><br>2. Aldosteron;<br /><br>3. 25-hydroxycholecalciferol;<br /><br>4. Alkaline phosphatase;<br /><br>5. Parathyroid hormone;<br /><br>6. The need of adjusting the antihypertensive therapy.
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