Familial Barrett's Esophagus
- Conditions
- Barrett's EsophagusGeneticsEsophageal Adenocarcinoma
- Registration Number
- NL-OMON22205
- Lead Sponsor
- niversity Medical Center Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Index patients of families that full fill one of the following diagnostic criteria for familial Barrett's esophagus or adenocarcinoma of the gastro-esophageal junction:
A. Two or more first- or second degree relatives with BE or adenocarcinoma of the GEJ, with at least one diagnosed before the age of 50
Exclusion Criteria
A potential individual who meets any of the following criteria will be excluded from participation in this study:
1) Individuals < 25 and > 75 years old
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Determine the prevalence of BE among first degree relatives of index patients of families that fulfil criteria for familial BE/adenocarcinoma of the GEJ<br><br /><br /><br>Determine the number and type of (pre) malignant lesions in first degree relatives of index patients of families that fulfil criteria for familial BE/adenocarcinoma of the GEJ
- Secondary Outcome Measures
Name Time Method