NCT03561831已完成不适用
Evaluation the Effects of Anaesthetic Agents on Endoplasmic Reticulum Stress During Cancer Surgery
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 53
- 试验地点
- 1
- 主要终点
- Change in endoplasmic reticulum stress
研究概览
简要总结
Investigate the change in endoplasmic reticulum stress after cancer surgery according to different anaesthetics including propofol and sevoflurane.
详细描述
We hypothesize propofol and sevoflurane based anesthesia would show different pattern of endoplasmic reticulum stress after cancer surgery in patients with cancer
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Basic Science
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •patients with cancer
排除标准
- •age under 19 years old
- •allergy history to propofol or sevoflurane
- •history of previous cancer
研究组 & 干预措施
propofol group
Active Comparator
patients who anesthesized by propofol
干预措施: Propofol (Drug)
sevoflurane group
Active Comparator
patients who anesthesized by sevoflurane
干预措施: Sevoflurane (Drug)
结局指标
主要结局
Change in endoplasmic reticulum stress
时间窗: baseline, postoperative 1 hours and 24 hours
Change in endoplasmic reticulum stress
次要结局
未报告次要终点
研究者
Seong-Hyop Kim
Professor
Konkuk University Medical Center
研究点 (1)
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