NCT03561831
Completed
Not Applicable
Evaluation the Effects of Anaesthetic Agents on Endoplasmic Reticulum Stress During Cancer Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Propofol
- Conditions
- Endoplasmic Reticulum Stress
- Sponsor
- Konkuk University Medical Center
- Enrollment
- 53
- Locations
- 1
- Primary Endpoint
- Change in endoplasmic reticulum stress
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
Investigate the change in endoplasmic reticulum stress after cancer surgery according to different anaesthetics including propofol and sevoflurane.
Detailed Description
We hypothesize propofol and sevoflurane based anesthesia would show different pattern of endoplasmic reticulum stress after cancer surgery in patients with cancer
Investigators
Seong-Hyop Kim
Professor
Konkuk University Medical Center
Eligibility Criteria
Inclusion Criteria
- •patients with cancer
Exclusion Criteria
- •age under 19 years old
- •allergy history to propofol or sevoflurane
- •history of previous cancer
Arms & Interventions
propofol group
patients who anesthesized by propofol
Intervention: Propofol
sevoflurane group
patients who anesthesized by sevoflurane
Intervention: Sevoflurane
Outcomes
Primary Outcomes
Change in endoplasmic reticulum stress
Time Frame: baseline, postoperative 1 hours and 24 hours
Change in endoplasmic reticulum stress
Study Sites (1)
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