Comparison Between IPRF With Vit. C and IPRF Alone in Management of ID'Pain

Not Applicable

Completed

• Conditions: TMJ Pain
• Interventions: Other: Injectable platelet rich fibrin; Drug: Vitamin C

• Registration Number: NCT06345092
• Lead Sponsor: Cairo University

Brief Summary

Randomized clinical trial between 2groups,the study group to be injected in the TMJ with injectable platelet rich fibrin with vitamin C and the control group to be injected in the TMJ with injectable platelet rich fibrin alone in management of internal Temporomandibular joint derangement

Detailed Description

Randomized clinical trial between 2groups,the study group to be injected in the TMJ with injectable platelet rich fibrin with vitamin C and the control group to be injected in the TMJ with injectable platelet rich fibrin alone in management of internal Temporomandibular joint derangement

Study Timeline

• Study First Submitted: 2024-03-26
• Study First Submitted QC: 2024-04-01
• Study First Posted: 2024-04-03
• Study Start: 2024-04-15
• Primary Completion: 2024-05-15
• Study Completion: 2024-08-15
• Status Verified: 2024-11
• Last Update Submitted: 2024-11-07
• Last Update Posted: 2024-11-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Patients with internal TMJ derangement (anterior disc displacement with reduction)

Exclusion Criteria

Pathological conditions ; trauma TMJ cases or any blood diseases

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
control group	Injectable platelet rich fibrin	injection of injectable platelet rich fibrin alone
intervention group	Injectable platelet rich fibrin	injection of injectable platelet rich fibrin with vitamin C
intervention group	Vitamin C	injection of injectable platelet rich fibrin with vitamin C

Primary Outcome Measures

Name	Time	Method
Pain management	at 4;8;12;16 weeks	Evaluation of pain using VAS pre and post injections

Secondary Outcome Measures

Name	Time	Method
disc position using MRI	at 4;8;12;16 weeks	evaluation of disc position pre and post injections

Trial Locations

Locations (1)

Faculty of Dentistry cairo university; 🇪🇬 Cairo, Egypt