Comparing the efficacy of ketamine and paracetamol in reducing pain due to propofol injection during induction of general anaesthesia

Completed

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2019/09/021299
• Lead Sponsor: DRSHAJI MATHEW

Brief Summary

Propofol short acting intravenous anaesthetic agent is extensively used because of its smooth induction and recovery .Its a agent of choice in day care anaesthesia ,for sedation in ICU,as maintenance agent in anaesthesia.However pain due to this is major drawback.Various strategies have been practiced to reduce pain  like choosing a larger vein,cooling propofol,dilution of propofol,increasing speed of injection.

Ketamine and paracetamol are good analgesic properties so in this study comparing between two which provides better pain relief.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-09-25
• Study Completion: 2020-02-10
• Last Update Posted: 2020-12-11

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

American Society of Anesthesiologists physical status (ASAPS) I and II patients undergoing elective surgeries under general anaesthesia.

Exclusion Criteria

Suspected allergy to propofol,ASAPS 3 and 4,patient refusal,emergency surgeries.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
to observe for pain reduction immediately after administration of 1/3rd dose of propofol then 1 min and 2 min	to observe for pain reduction immediately after administration of 1/3rd dose of propofol then 1 min and 2 min

Secondary Outcome Measures

Name	Time	Method
to observe for hemodynamic changes if any before administering drug ,after intubation ,5 mins after intubation ,10 mins after intubation	0,5,10 mins

Trial Locations

Locations (1)

kasturba hospital; 🇮🇳 Udupi, KARNATAKA, India

kasturba hospital

🇮🇳Udupi, KARNATAKA, India

DR RESHMI M

Principal investigator

9791808837

reshmim91@gmail.com