POSTOPERATIVE ANALGESIC EFFECT OF INTRAPERITONEAL ROPIVACAINE WITH AND WITHOUT MAGNESIUM SULFATE IN LAPAROSCOPIC CHOLECYSTECTOMY-A PROSPECTIVE OBSERVATIONAL STUDY
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 44
- Locations
- 1
- Primary Endpoint
- To assess the
Study Overview
Brief Summary
the study is to compare the duration of analgesia and incidence of pain after intraperitoneal instillation of ropivacaine with and without magnesium sulphate in patints undergoing elective laparoscopic cholecystectomy,secondarily the study aims to note the post drug instillation hemodynamics,incidence and severity of postoperative nausea and vomiting
Study Design
- Study Type
- Interventional
- Allocation
- Computer generated randomization
- Masking
- Participant, Investigator, Outcome Assessor and Date-entry Operator Blinded
Eligibility Criteria
- Ages
- 25.00 Year(s) to 65.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •PATIENTS WHO ARE ASA CLASS 1 OR 2 UNDERGOING ELECTIVE LAPROSCOPIC SURGERY BMI -18 TO 30.
Exclusion Criteria
- •PATIENT WITH ECG SHOWING CONDUCTION ABNORMALITIES PREGNANT AND BREASTFEEDING PATIENT ON BETA BLOCKERS PATIENT WITH CHRONIC PAIN ON OPIOIDS AND OTHER ANALGESICS HISTORY OF ALLERGY TO STUDY DRUGS SURGERY DURATIONS MORE THAN THREE HOURS CONVERSION TO OPEN PROCEDURE EMERGENCY CHOLYCYSTECTOMY PATIENTS REQUIRING COMMON BILE DUCT EXPLORATION.
Outcomes
Primary Outcomes
To assess the
Time Frame: baseline,1 hour,2hour.6 hour,12 hour,24 hour
1.duration of analgesia after intraperitoneal instillation of ropivacaine with and without magnesium sulphate,
Time Frame: baseline,1 hour,2hour.6 hour,12 hour,24 hour
3.total doses of rescue analgesics in each groups
Time Frame: baseline,1 hour,2hour.6 hour,12 hour,24 hour
4.type of pain.
Time Frame: baseline,1 hour,2hour.6 hour,12 hour,24 hour
2.Mean pain scores during 24 hour ,
Time Frame: baseline,1 hour,2hour.6 hour,12 hour,24 hour
Secondary Outcomes
- Secondary objective(To study the post instillation hemodynamic changes in terms of heart rate(HR), systolic blood pressure(SBP), diastolic blood pressure(DBP), Oxygen saturation (SpO2), End Tidal Co2 (EtCO2) and postoperative nausea and vomiting(PONV))