A Study to compare the efficacy of Ropivacaine alone vs ropivacaine with dexmedetomidine for post operative analgesia in laparoscopic cholecystectomy.

Active, not recruiting

• Conditions: Calculus of gallbladder without cholecystitis, (2) ICD-10 Condition: K800||Calculus of gallbladder with acutecholecystitis, (3) ICD-10 Condition: K801||Calculus of gallbladder with othercholecystitis,

• Registration Number: CTRI/2023/05/052379
• Lead Sponsor: HINDU RAO HOSPITAL AND NORTH DMC MEDICAL COLLEGE

Brief Summary

This study aims to improve post operative analgesia for laparoscopic cholecystectomy. Intraperitoneal instillation of local anesthetic agents provide post operative analgesia in laparoscopic  cholecystectomy. The study will compare intraperitoneal instillation of ropivacaine to dexmedetomidine plus ropivacaine for post operative analgesia in laparoscopic cholecystectomy.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2023-07-08
• Study Start: 2023-08-05

Recruitment & Eligibility

• Status: Closed to Recruitment of Participants
• Sex: All
• Target Recruitment: 94

Inclusion Criteria

• Patient undergoing elective laparoscopic cholecystectomy 2.
• Patient belonging to ASA physical status grade 1 and grade 2.

Exclusion Criteria

• Patients refusing to participate in the study.
• Patients with known allergy to drugs used in the study.
• Patient with basal heart rate <60 beats per minute.
• Patient with suspected malignancy 5.
• Patient having abdominal drain at the end of surgery.
• patient with history of cardiac , respiratory, renal or hepatic disease.
• Pregnant Females.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To measure VAS score for post operative pain	1)T0- Time at arrival of patient in PACU | 2)T1- 30 minutes after arrival in PACU | 3)T2- 60 minutes after arrival in PACU | 4)T3- 120 minutes after arrival in PACU | 5)T4- 240 minutes after arrival in PACU | 6)T5- 360minutes after arrival in PACU | 7)T6- 720 minutes after arrival in PACU

Secondary Outcome Measures

Name	Time	Method
1) to measure time interval to first dose of rescue analgesia and total dose of rescue analgesia	2) to measure hemodynamic parameters in both groups

Trial Locations

Locations (1)

HINDU RAO HOSPITAL; 🇮🇳 North, DELHI, India

HINDU RAO HOSPITAL

🇮🇳North, DELHI, India

DR ALKA CHANDRA

Principal investigator

9560044454

dralkadelhi@yahoo.co.in