COMPARISON OF INTRAPERITONEAL INSTILLATION WITH ROPIVACAINE ALONE AND ROPIVACAINE PLUS DEXMEDETOMIDINE FOR POST OPERATIVE ANALGESIA IN LAPAROSCOPIC CHOLECYSTECTOMY
Trial Snapshot
- Phase
- Not Applicable
- Status
- Active, not recruiting
- Sponsor
- Enrollment
- 94
- Locations
- 1
- Primary Endpoint
- To measure VAS score for post operative pain
Study Overview
Brief Summary
This study aims to improve post operative analgesia for laparoscopic cholecystectomy. Intraperitoneal instillation of local anesthetic agents provide post operative analgesia in laparoscopic cholecystectomy. The study will compare intraperitoneal instillation of ropivacaine to dexmedetomidine plus ropivacaine for post operative analgesia in laparoscopic cholecystectomy.
Study Design
- Study Type
- Interventional
- Allocation
- Computer generated randomization
- Masking
- Participant and Outcome Assessor Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 60.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Patient undergoing elective laparoscopic cholecystectomy
- •Patient belonging to ASA physical status grade 1 and grade 2.
Exclusion Criteria
- •Patients refusing to participate in the study.
- •Patients with known allergy to drugs used in the study.
- •Patient with basal heart rate <60 beats per minute.
- •Patient with suspected malignancy
- •Patient having abdominal drain at the end of surgery.
- •patient with history of cardiac , respiratory, renal or hepatic disease.
- •Pregnant Females.
Outcomes
Primary Outcomes
To measure VAS score for post operative pain
Time Frame: 1)T0- Time at arrival of patient in PACU | 2)T1- 30 minutes after arrival in PACU | 3)T2- 60 minutes after arrival in PACU | 4)T3- 120 minutes after arrival in PACU | 5)T4- 240 minutes after arrival in PACU | 6)T5- 360minutes after arrival in PACU | 7)T6- 720 minutes after arrival in PACU
Secondary Outcomes
- 1) to measure time interval to first dose of rescue analgesia and total dose of rescue analgesia(2) to measure hemodynamic parameters in both groups)
