Skip to main content
MedPath Trial logoMedPath TrialMedPath Trial Home
Clinical Trials/CTRI/2023/05/052379
CTRI/2023/05/052379Active, not recruitingNot Applicable

COMPARISON OF INTRAPERITONEAL INSTILLATION WITH ROPIVACAINE ALONE AND ROPIVACAINE PLUS DEXMEDETOMIDINE FOR POST OPERATIVE ANALGESIA IN LAPAROSCOPIC CHOLECYSTECTOMY

HINDU RAO HOSPITAL AND NORTH DMC MEDICAL COLLEGE1 site in 1 country94 target enrollmentStarted: August 5, 2023Last updated:
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Active, not recruiting
Sponsor
Enrollment
94
Locations
1
Primary Endpoint
To measure VAS score for post operative pain
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

This study aims to improve post operative analgesia for laparoscopic cholecystectomy. Intraperitoneal instillation of local anesthetic agents provide post operative analgesia in laparoscopic  cholecystectomy. The study will compare intraperitoneal instillation of ropivacaine to dexmedetomidine plus ropivacaine for post operative analgesia in laparoscopic cholecystectomy.

Study Design

Study Type
Interventional
Allocation
Computer generated randomization
Masking
Participant and Outcome Assessor Blinded

Eligibility Criteria

Ages
18.00 Year(s) to 60.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • •Patient undergoing elective laparoscopic cholecystectomy
  • •Patient belonging to ASA physical status grade 1 and grade 2.

Exclusion Criteria

  • •Patients refusing to participate in the study.
  • •Patients with known allergy to drugs used in the study.
  • •Patient with basal heart rate <60 beats per minute.
  • •Patient with suspected malignancy
  • •Patient having abdominal drain at the end of surgery.
  • •patient with history of cardiac , respiratory, renal or hepatic disease.
  • •Pregnant Females.

Outcomes

Primary Outcomes

To measure VAS score for post operative pain

Time Frame: 1)T0- Time at arrival of patient in PACU | 2)T1- 30 minutes after arrival in PACU | 3)T2- 60 minutes after arrival in PACU | 4)T3- 120 minutes after arrival in PACU | 5)T4- 240 minutes after arrival in PACU | 6)T5- 360minutes after arrival in PACU | 7)T6- 720 minutes after arrival in PACU

Secondary Outcomes

  • 1) to measure time interval to first dose of rescue analgesia and total dose of rescue analgesia(2) to measure hemodynamic parameters in both groups)

Investigators

Sponsor
HINDU RAO HOSPITAL AND NORTH DMC MEDICAL COLLEGE
Sponsor Class
Government medical college

Study Sites (1)

Loading locations...

Similar Trials

Completed
Not Applicable
Intraperitoneal Analgesia After Laparoscopic CholecystectomyLaparoscopic Cholecystectomy
NCT00950625Aga Khan University200
Completed
Not Applicable
Comparison of Intraoperative Intravenous Lidocaine Infusion and Transversus Abdominis Plane (TAP) Block for Post-operative Analgesia Following Laproscopic CholecystectomyPost Operative Pain
NCT05231941Aga Khan University Hospital, Pakistan90
Not yet recruiting
Unknown
Comparing pain relief property of bupivacaine alone and bupivacaine with dexmedetomidine when given inside abdomen after operation of gall bladder with laparoscopic methodOther cholelithiasis,
CTRI/2020/10/028678Vivek Vishal60
Not yet recruiting
Not Applicable
To compare the effects of two drug groups, levobupivacaine and dexmedetomidine with ropivacaine and dexmedetomidine for intraperitoneal injection after laparoscopic gall bladder removal.
CTRI/2022/07/044455JLN medical college Ajmer60
Active, not recruiting
Phase 4
Postoperative pain relief and analgesia after laproscopic cholecystectomy: bupivacaine versus nalbuphine ,when instilled through the laprpscopic portAdministration, (2) ICD-10 Condition: K800||Calculus of gallbladder with acutecholecystitis,
CTRI/2020/11/028869Hakeem Abdul Centenary hospitalNew Delhi80