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Imaging of plasticity in circuits of the forebrain: biomarkers, pathophysiology, and genetic mechanisms

Recruiting
Conditions
F20
Schizophrenia
Registration Number
DRKS00004255
Lead Sponsor
Zentralinstitut für Seelische Gesundheit
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
190
Inclusion Criteria

Right-handedness, German natives
-Ability to understand and accept study protocol
-For patients: Diagnosis of schizophrenia (DSM-IV criteria)
-For Relatives: Validated diagnosis by medical staff

Exclusion Criteria

-MRI-exclusion criteria (metal parts in body, brain operations, permanent make-up)
-Migration background
-Psychiatric diagnosis in controls and relatives

Study & Design

Study Type
observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
a) Acquisition of data<br>b) Identifikation of biomarkers and their (genetic) modulation<br>c) Identifikation of defizits in those biomarkers in schizophrenic patients<br><br>
Secondary Outcome Measures
NameTimeMethod
Development of new strategies to analyze data<br><br>
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