Outcomes and Neural Mechanisms of Emotion Regulation Therapy in Young Adults With Autism: A Pilot Feasibility Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Autism
- Sponsor
- Michal Assaf
- Enrollment
- 5
- Locations
- 1
- Primary Endpoint
- Adult Self Report (ASR)
- Status
- Recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
This pilot study is designed to investigate the clinical outcomes and neural mechanisms of emotion regulation behavioral treatment , in a small sample of young adults diagnosed with autism spectrum disorder.
Detailed Description
Five young adults with ASD with emotional/behavioral challenges that are attributed to emotion dysregulation will be enrolled into an emotion regulation (ER) intervention administered twice weekly for a total of 16 sessions. Participants will be evaluated pre- and post-treatment using behavioral and imaging measures, and at mid-treatment and 2-month follow-up using behavioral measures administered electronically and/or via phone interview.
Investigators
Michal Assaf
Director, Autism & Functional Mappin lab
Hartford Hospital
Eligibility Criteria
Inclusion Criteria
- •Diagnosis of Autism Spectrum Disorder
- •Ages 18-40
- •Estimated full-scale IQ ≥ 80
- •T score \> 60 on either the externalizing or internalizing symptoms scores of either the Adult Behavior Checklist (ABC-L) or the Adult Self Report (ASR)
- •Participation in previous study at the Olin Center ("Social Emotional Study"; E-HHC- 2018-0241)
Exclusion Criteria
- •Intellectual disability (estimated full scale IQ\<80
- •History of a significant head injury (severe concussion, hospitalization)
- •History of neurosurgery
- •History of epilepsy, stroke, MS, a neurodegenerative disorder, or any other neurological disorder
- •A current major medical condition (e.g. cancer, heart failure)
- •Current substance use (determined by urine screen done to all participants before each MRI scan)
- •In-body metal implants (e.g. surgical clips, certain pacemakers) or history of exposure to metal shards or other MRI contraindications
- •Pregnancy
Outcomes
Primary Outcomes
Adult Self Report (ASR)
Time Frame: 2 months follow-up
Externalizing and internalizing composite scores
Adult Behavior Checklist (ABC-L)
Time Frame: 2 months follow-up
Externalizing and internalizing composite scores