Comparision of two drugs viz; clonidine and dexmeditomidine for lowering blood pressure in surgical correction of facial bones.
- Conditions
- Facial deformity
- Registration Number
- CTRI/2018/08/015217
- Lead Sponsor
- Department of Anaesthesiology
- Brief Summary
A randomised controlled trial to see the efficacy of two anaesthesia drugs, Intavenous clonidine and dexmeditomidine, in its abitity to produce controlled hypotension in patients undergoing orthognatic surgery. The study will be conducted in the Centre for Dental Education and Research, All India Institute of Medical Sciences. Patients of 18 to 60 years age group, belonging to ASA physical status 1 coming for elective orthognatic surgery will be enrolled in the study. Total of 20 patients will be enrolled in the study over a period of 1-2 year ( based on the annual turnover of the centre). Patients will be randomised according to computer generated random numbers. The total amount of each drug used in the intraoperative period will be calculated. Also the amount of rescue analgesia needed, amount of blood loss, quality of surgical field, and any oher adverse events will be noted. Results will be analysed by an independent investigator and appropriate statistical tools applied.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 20
American society of anesthesiologists physical status 1 Elective orthognatic surgery.
Associated comorbidities Known allergy or contraindication to the use of any of the drugs Patients requiring awake intubation.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Intraoperative vital parameters ( Heart rate, systolic blood pressure, diastolic blood pessure, mean arterial pressure) every 15 minutes till end of surgery
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
operation theatre complex, Centre for Dental Education and Research
🇮🇳Delhi, DELHI, India
operation theatre complex, Centre for Dental Education and Research🇮🇳Delhi, DELHI, IndiaDevalina GoswamiPrincipal investigator9971196699drdevalina@gmail.com