Short term effects of high polyphenol content chocolate on blood vessel health

Completed

• Conditions: Type 2 diabetes; Nutritional, Metabolic, Endocrine; Non-insulin-dependent diabetes mellitus

• Registration Number: ISRCTN35988358
• Lead Sponsor: Barry Callebaut (Belgium)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2009-09-22
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

1. Male or post menopausal female, aged between 40-75
2. Type 2 diabetes
3. Managed with diet or exercise alone or metformin
4. Stable medication

Exclusion Criteria

1. Unwilling to allow contact with GP
2. Diabetes treated with other agents

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improved endothelial function as measured by EndoPAT™. Endothelial function was assessed before consumption of the chocolate, then at 60 and 180 min following consumption of the chocolate.

Secondary Outcome Measures

Name	Time	Method
1. Insulin response <br>2. C-reactive protein (CRP)<br><br>The secondary outcomes were measured before consumption of the chocolate, then every 30 min until 180 min after consumption of the chocolate.