Effectiveness of reduction of WBCs in blood bags prepared at cold temperature in comparison to those prepared at room temperature.
Phase 3
- Conditions
- Health Condition 1: T808- Other complications following infusion, transfusion and therapeutic injectionHealth Condition 2: null- Reduction in incidence of febrile non hemolytic transfusion reaction after transfusion of LDRC bags processed at 4 degree Celsius in comparison to those processed at 22 degree Celsius
- Registration Number
- CTRI/2015/08/006116
- Lead Sponsor
- Christian Medical College and Hospital Vellore
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Closed to Recruitment of Participants
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients, of any age and gender, requiring Leukodepleted red cell blood bags (LDRCs) are alloted the same, these mainly constitute nephrology and cardiothoracic surgery patients.
The decision to transfuse LDRC blood bag to a patient is mainly dependent on the decision of the clinician/treating doctor or blood bank medical officer towards the benefit of the patient, and also on the availability of LDRC bags in blood bank.
Exclusion Criteria
•Patients on antipyretic medication.
•Patients with co-existing febrile illness.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mean reduction in number of residual WBCs achieved in LDRC bags processed at 4 degree Celsius as compared to 22 degree Celsius.Timepoint: 4 weeks
- Secondary Outcome Measures
Name Time Method Incidence of febrile non haemolytic transfusion reactions in patients transfused with LDRC bags processed at 4 degree Celsius in comparison to those processed at 22 degree Celsius.Timepoint: 32 months