Comparison of efficacy of two drug combinations (ketodex vs ketofol) for sedation in colonoscopic procedures
Not Applicable
- Conditions
- Health Condition 1: K00-K95- Diseases of the digestive system
- Registration Number
- CTRI/2020/07/026622
- Lead Sponsor
- Rashi sarna
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ï??1. ASA I-II
2. Age group of 21-65years
3. Both gender
4. Patients with BMI (25-35 kg/m2)
5. Scheduled to undergo colonoscopy in gastroenterology department
Exclusion Criteria
1.Acute Respiratory tract infections
2.Predicted difficult airway
3.History of allergy to propofol, ketamine or dexmedetomidine
4.Patients on sedatives within two weeks prior tosurgery
ï??5.Altered mental status (psychiatric and anxiety disorder)
ï??6.Patients with chronic pain or on painkiller.
ï??7.Patients with severe hepatic or kidney impairment
ï??8.Pregnant or breast feeding female
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Efficacy of sedation based on intraoperative patient movement scoreTimepoint: The movement score will be seen <br/ ><br>at T0(baseline), T1 (2.5mins), T2(5mins),T3 (10mins).T4(15mins),T5(20mins),T6(25mins),T7(30mins)
- Secondary Outcome Measures
Name Time Method ï?¼1.Effect on hemodynamics and respiratorydepression <br/ ><br>ï?¼2.Recovery time fromsedation <br/ ><br>ï?¼3.Postoperative Pain Score (Visual AnalogueScore) <br/ ><br> <br/ ><br>Timepoint: â?¢HR, BP, RR, SpO2 will be noted every 5 minutes interval <br/ ><br>The patients will be observed for 1â??2 hours until the patientâ??s Aldrete score 9